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Prednisone (Anti-Allergic)

Prednisone is a synthetic corticosteroid, used for suppressing the immune system and inflammation. Prednisone usually taken orally but can be delivered by intramuscular injection and can be used for a great number of different conditions.
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Prednisone

Prednisone is used in the management of inflammatory conditions or diseases in which the immune system plays an important role.

Prednisone is particularly effective as an immunosuppressant, and affects virtually all of the immune system. It can, therefore, be used in autoimmune diseases, inflammatory diseases (such as severe asthma, severe allergies, severe poison ivy dermatitis, systemic lupus erythematosus, ulcerative colitis, rheumatoid arthritis, Bell's Palsy, Crohn's disease, pemphigus and sarcoidosis), various kidney diseases including nephrotic syndrome, and to prevent and treat rejection in organ transplantation.

Prednisone is used as replacement therapy in patients whose adrenal glands are unable to produce sufficient amounts of cortisol.

How Taken

Tablets of 2.5, 5, 10, 20, and 50 mg. Oral solution or syrup of 5mg/5ml. The initial dose of Prednisone varies depending on the condition being treated and the age of the patient. The starting dose may be from 5 to 60 mg per day and often is adjusted based on the response of the condition being treated. Corticosteroids typically do not produce immediate effects and must be used for several days before maximal effects are seen.

Side Effects

Short-term side-effects, as with all glucocorticoids, include high blood glucose levels, especially in patients that already have diabetes mellitus or are on other medications that increase blood glucose (such as tacrolimus), and mineralocorticoid effects such as fluid retention (although it is worth noting, however, that the mineralocorticoid effects of Prednisone are very minor; this is why it is not used in the management of adrenal insufficiency unless a more potent mineralocorticoid is administered concomitantly). Additional short-term side-effects include insomnia, euphoria, and, rarely, mania. Long-term side-effects include Cushing's syndrome, weight gain, osteoporosis, glaucoma, type II diabetes mellitus, and depression upon withdrawal.

Missed Dose

If you take one dose daily, take the missed dose as soon as you remember. However, if you don't remember until the next day, skip the dose you missed and take only your regular daily dose. If you take more than one dose daily, you can either take the missed dose as soon as you remember, or you can take two doses at the next dose time. If you take one dose every other day, take the missed dose as soon as you remember, then go back to your regular every-other-day schedule.

Storage

Store at room temperature 20-25 degrees C (68-77 degrees F), and keep away from moisture.

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